CRS Scientist Spotlight on Dr. Jennifer Bakkensen

Dr. Jennifer Bakkensen, MD, is a clinical fellow in Reproductive Endocrinology and Infertility.  Her research focuses on changes in ovarian cumulus cells and follicular fluid that occur with physiologic and pathologic ovarian aging.

What brought you to join the CRS community and what is your current position? 

I am a clinical fellow in Reproductive Endocrinology and Infertility (REI). My research focus throughout residency and fellowship has been largely clinical; however, I was drawn to the CRS community by my mentor, Dr. Kara Goldman, after learning about some of the exciting opportunities for translational research that align closely with my clinical interests. 

Could you describe what your work entails? 

I am interested in evaluating changes in ovarian cumulus cells and follicular fluid that occur with physiologic and pathologic ovarian aging. The Goldman lab studies the mTOR pathway and its role in reproductive aging. We are interested in expanding this body of work through proteomic analysis of key markers of mTOR activation in cumulus cells and follicular fluid among patients undergoing ovarian stimulation and oocyte retrieval. Furthermore, we are interested in identifying other proteins that appear to be upregulated or downregulated in these tissues with ovarian aging to identify other potential targets and pathways for future research.  

What aspect(s) of CRS do you find most valuable?  

There are so many smart people with varied backgrounds and experiences doing amazing work at CRS. The opportunities to learn from and collaborate with mentors and colleagues is really special. 

What has been the most valuable aspect to your work in reproductive science? 

As a clinician, the opportunity to gain a deeper understanding of the basic science and translational research that underpins every major advancement in our field is a critical aspect of my training, and one that will equip me to better interpret and evaluate the literature throughout my career.  

What would you recommend to students and young professionals in order for them to succeed in their careers? ​  

Find mentors who inspire you and will help you align your personal and professional goals and interests. And don’t be afraid to step outside of your comfort zone.  

What do you think will be the next big contribution in the reproductive biology field?  

There are so many developing technologies with the potential to forever change reproductive biology in my lifetime, from gene-editing as it pertains to pre-implantation embryos to in vitro gametogenesis as a means of circumventing reproductive aging. I feel certain that I will not be practicing reproductive medicine the same way I do today 20 years from now. That is one of the things I love about this field! 

What hobbies do you have outside of the lab?   

I love to travel and have recently been enjoying the beauty of our national parks. Closer to home, I love visiting different neighborhoods, exploring the culture, history, and food of each. And few things bring me greater joy than a leisurely stroll to my neighborhood cafe for a breakfast sandwich and a coffee on a Saturday morning with my family.